AGO cell lines
AGO1
Prof. A. Piton has created a central repository of samples at the University Hospital of Strasbourg, France. We are extremely grateful to all donor families and physicians who contributed materials.
Available cell lines
4 fibroblast cell lines
2 induced pluripotent stem cell lines (iPSCs) carrying the G199S variant introduced by CRISPR/Cas9 editing
Please contact Prof. Amélie Piton at piton@igbmc.fr for further information
if you are a patient family and would like to donate a tissue sample,
if you are a researcher and would like to discuss your research or obtain a Material Transfer Agreement.
AGO2
Prof. Lessel has created a central repository of samples at the University Hospital Salzburg, Austria. We are extremely grateful to all donor families and physicians who contributed materials.
Available cell lines
4 fibroblast cell lines (P192L, A376P, D619N, G733R)
2 induced pluripotent stem cells (iPSCs; P192L, G733R)
Please contact Prof. Davor Lessel at d.lessel@salk.at for further information
if you are a patient family and would like to donate a tissue sample,
if you are a researcher and would like to discuss your research or obtain a Material Transfer Agreement.
AGO animal models
AGO1
Prof. A. Zinovyeva and Prof. V. Ambros have established and characterized 4 C. elegans worm models (Duan et al. bioRxiv 2023):
alg-1(ma447, F180Δ), alg-1(ma443, G199S), alg-1(zen25, V254I), alg-1(zen18, H751L)
Please contact Prof. Zinovyeva at zinovyeva@ksu.edu for collaborations or to request a strain.
AGO2
A mouse model is currently being characterized at University Medical Center Hamburg-Eppendorf (UKE), Germany. This study is led by Professor Kreienkamp.
Please contact Dr. Davor Lessel at d.lessel@salk.at for further information.